卫功宏
职 称🤵🏻♂️：教授
电 话：021-54237291
电子邮箱：gonghong_wei@fudan.edu.cn
办公地点：上海市徐汇东安路131号东1号楼345
个人主页/课题组网页👩🏻💼：/biochemisry/da/53/c29856a318035/page.htm
教育经历
工作经历
获得人才项目
获得奖项
研究方向
科研项目
课程讲授
学术兼职
代表性论著
1996.09—2000.07 安徽师范大学生命科学杏鑫本科
2000.09—2003.07 首都师范大学生命科学杏鑫硕士
2003.08—2006.09 北京协和医杏鑫基础杏鑫博士
2006.10—2011.10 芬兰赫尔辛基大学医杏鑫博士后
2011.11—2019.11 芬兰奥卢大学医杏鑫青年研究员、副教授、教授
2014.9—2019.8 芬兰科杏鑫研究员
2016.9—2019.11Cancer Genomics Unit Leader
2019.11—至今 杏鑫特聘教授
2021.10—至今 杏鑫生物化学与分子生物学系主任
2019，国家重点联系专家
2019，上海市海外高层次人才
2019，Medix Prize
2018，Biocenter Oulu Discovery of the Year
2017🎐，Excellent doctoral thesis award of University of Oulu Medical School
2016👩🏻🔧，Biocenter Oulu Discovery of the Year
2015，Medix Prize
2014，Biocenter Oulu Discovery of the Year
2009，国际生化大会（IUBMB&FAOBMB）Pfizer最佳壁报奖
2006，北京协和医杏鑫优秀研究生(基础杏鑫)
基因表达调控与人类疾病
医学遗传学与基因组学
表观遗传与系统生物学
2021，国家自然科学基金委面上项目，主持
临床医学专业六年制MBBS全英文授课《Biochemistry》
预防班专业五年制授课《生物化学》
2021-2022 Frontiers in Oncology Special Issue Guest Editor
2018-今 Asian Journala of UrologyAssociate Editor
2018-今 Scientific ReportsEBM
2018-今Society of Chinese Bioscientists in America (SCBA) Life International Membership
2015-2019Finnish Connective Tissue Society Membership
Nikolaos Giannareas1#, Qin Zhang1#, Xiayun Yang1#, Rong Na2#, Yijun Tian3, Yuehong Yang1, Xiaohao Ruan4, Da Huang4, Xiaoqun Yang5, Chaofu Wang5, Peng Zhang6, Aki Manninen1, Liang Wang4, Gong-Hong Wei*. Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG. Nature Communications. accepted
Zhang N, Huang D, Jiang G, Chen S, Ruan X, Chen H, Huang J, Liu A, Zhang W, Lin X, Wu Y, Zhang Q, Li J, Tsu JH*, Wei GH*, Na R*. Genome-Wide 3'-UTR Single Nucleotide Polymorphism Association Study Identifies Significant Prostate Cancer Risk-Associated Functional Loci at 8p21.2 in Chinese Population. Adv Sci(Weinh). 2022 Aug;9(23):e2201420.
Chen Y, Zhang P, Liao J, Cheng J, Zhang Q, Li T, Zhang H, Jiang Y, Zhang F, Zeng Y, Mo L, Yan H, Liu D, Zhang Q, Zou C*, Wei GH*, Mo Z*. Single-cell transcriptomics reveals cell type diversity of human prostate. J Genet Genomics. 2022 Apr 6:S1673-8527(22)00090-X (cover story).
Tian P#, Zhong M#, Wei GH*. Mechanistic insights into genetic susceptibility to prostate cancer. Cancer Letters. 2021 Sep 22; 522:155-163.
Ahmed M#, Soares F#, Xia JH#, Yang Y, Li J, Guo H, Su P, Tian Y, Lee JH, Wang M, Akhtar N, Houlahan KE, Bosch A, Zhou S, Mazrooei P, Hua J, Chen S, Petricca J, Zeng Y, Davies A, Fraser M, Quigley DA, Feng F, Boutros PC, Lupien M, Zoubeidi A, Wang L, Walsh MJ, Wang T, Ren S*, Wei GH*, He HH*. CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer, Nature Communications. 2021 Mar 19; 12(1):1781.
Gao P#, Xia JH#, Sipeky C, Dong XM, Zhang Q, Yang Y, Zhang P, Cruz SP, Zhang K, Zhu J, Lee HM, Suleman S, Giannareas N, Liu S; PRACTICAL Consortium, Tammela TLJ, Auvinen A, Wang X, Huang Q, Wang L, Manninen A, Vaarala MH, Wang L, Schleutker J, Wei GH*. Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus. Cell. 2018. 174:576-589.
Previewed in Bulger M. Changing the Guard at a Prostate Cancer SNP. Cell. 174:501-502, 2018
Highlighted in Bradley C. Mechanistic insights into a non-coding risk SNP. Nature ReviewsUrology15:655, 2018
Invited author's views: Xia JH & Wei GH. Oncogenic regulatory circuits driven by 19q13 rs11672691 underlies prostate cancer aggressiveness. Molecular & Cellular Oncology. 5(6):e1516451. 2018Huang Q#, Whitington T#, Gao P, Lindberg JF, Yang Y, Sun J, Väisänen MR, Szulkin R, Annala M, Yan J, Egevad LA, Zhang K, Lin R, Jolma A, Nykter M, Manninen A, Wiklund F, Vaarala MH, Visakorpi T, Xu J, Taipale J*, Wei GH*. A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding. Nature Genetics. 2014. 46:126-135.
Previewed in HOXB13, RFX6 and prostate cancer risk. Nature Genetics. 46:94-95, 2014
Highlighted in Prostate cancer: HOXB13 and a SNP collaborate to increase risk. Nature Reviews Urology. 11:64, 2014
Research Watch A Prostate Cancer–Associated SNP Increases HOXB13 Binding. Cancer Discovery4:268, 2014
Recommended by Faculty of 1000: ★★ Very Good, good for teaching, new finding. In F1000Prime, 27 Jan 2014; DOI: 10.3410/f.718228195.793490008
News in JNCI: Journal of the National Cancer Institute, 2014
Eturauhassyöpään johtava geenimuutos löytyi Oulussa. HELSINGIN SANOMAT Jan 10 2014Whitington T#, Gao P#, Song W, Ross-Adams H, Lamb AD, Yang Y, Svezia I, Klevebring D, Mills IG, Karlsson R, Halim S, Dunning MJ, Egevad L, Warren AY, Neal DE, Grönberg H, Lindberg J, Wei GH (joint supervision), Wiklund F. Gene regulatory mechanisms underpinning prostate cancer susceptibility. Nature Genetics. 2016. 48:387-397.
Research Watch Prostate Cancer Risk Loci Are Associated with Gene Regulatory Mechanisms. Cancer Discovery 6:OF13, 2016Zhang P#, Xia J#, Zhu J, Gao P, Tian YJ, Du M, Guo CY, Suleman S, Zhang Q, Kohli M, Tillmans L, Thibodeau SN, French AJ, Cerhan JR, Wang LD*, Wei GH*, Wang L*. High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing. Nature Communications. 2018. 9, 2022.
Sipeky C#, Gao P#, Zhang Q, Wang L, Ettala O, Talala K, Tammela TL, Auvinen A, Wiklund F, Wei GH*, Schleutker J*. Synergistic interaction of HOXB13 and CIP2A predispose to aggressive prostate cancer. Clinical Cancer Research. 2018. 15;24(24):6265-6276.
