Yang Liu, Xinyu Chen , Yunlong Ma , Chenyun Song, Jixin Ma, Cheng Chen , Jianzhong Su, Lixiang Ma*, Hexige Saiyin* Endogenous mutant Huntingtin alters the corticogenesis via lowering Golgi recruiting ARF1 in cortical organoid. Mol Psychiatry. 2024， doi: 10.1038/s41380-024-02562-0.
Chen Y, Jiao D, Liu Y, Xu X, Wang Y, Luo X, Saiyin H, Li Y, Gao K, Chen Y, Zhao SM*, Ma L*, Wang C*. FBXL4 mutations cause excessive mitophagy via BNIP3/BNIP3L accumulation leading to mitochondrial DNA depletion syndrome. Cell Death Differ. 2023 Aug 11. doi: 10.1038/s41418-023-01205-1.
Buhe H, Ma JX, Ye FZ, Song CY, Chen XY, Liu Y, Lin H, Han X, Ma LX*, Saiyin H*. IDO-1 inhibitor INCB24360 elicits distant metastasis of basal extruded cancer cells in pancreatic ductal adenocarcinoma. Acta Pharmacol Sin. 2023 Jun;44(6):1277-1289.
Song C, Chen X, Ma J, Buhe H, Liu Y, Saiyin H*, Ma L*. Construction of a pancreatic cancer nerve invasion system using brain and pancreatic cancer organoids. J Tissue Eng. 2023. doi: 10.1177/20417314221147113.
Chen X, Saiyin H, Liu Y, Wang Y, Li X, Ji R, Ma L. Human striatal organoids derived from pluripotent stem cells recapitulate striatal development and compartments. PLoS Biol. 2022 Nov 17;20(11):e3001868.
Li X, Saiyin H, Chen X, Yu Q, Ma L*, Liang W*. Ketamine impairs growth cone and synaptogenesis in human GABAergic projection neurons via GSK-3β and HDAC6 signaling. Mol Psychiatry. 2022 Nov 21. doi: 10.1038/s41380-022-01864-5.
Xu Han#, Lixiang Ma#, Jichun Gu#, Dansong Wang, Ji Li*, Wenhui Lou*,Hexige Saiyin*, Deliang Fu. Basal microvilli define the metabolic capacity and lethal phenotype of pancreatic cancer. Journal of Pathology. 2021 ;253(3):304-314.
Lixiang Ma, Xu Han , Jichun Gu, Ji Li , Wenhui Lou, Chen Jin, Hexige Saiyin. The physiological characteristics of the basal microvilli microvessels in pancreatic cancers. Cancer Medicine. 2020;9(15):5535-5545.
Yang W, Xie J, Qiang Q, Li L, Lin X, Ren Y, Ren W, Liu Q, Zhou G, Wei W, Saiyin H*, Ma L*. Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease. Neuroscience bulletin. 2019;35(6):1024-1034.
Yao Y, Cui X, Al-Ramahi I, Sun X, Li B, Hou J, Difiglia M, Palacino J, Wu ZY*, Ma L*, Botas J*, Lu B*. A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity. Elife. 2015 Mar 4;4: doi: 10.7554/eLife.05449.
Ma L, Hu BY, Liu Y, Vermilyea SC, Liu H, Gao L, Sun Y, Zhang X , Zhang SC: Human Embryonic Stem Cell-Derived GABA Neurons Correct Locomotion Deficits in Quinolinic Acid-Lesioned Mice, Cell Stem Cell . 2012;10, 455–464.
